Cutaneous reactions caused by injected immunomodulators in the treatment of multiple sclerosis and associated factors.
Objectives: to describe cutaneous reactions caused by injected immunomodulators used for the treatment of multiple sclerosis (MS) and associated factors. Methods: a descriptive and analytical cross-sectional study was conducted with a nonprobability sample of MS patients undergoing treatment at a ho...
| Publicado en: | Revista Eletrônica de Enfermagem Vol. 27; pp. 1 - 9 |
|---|---|
| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Revista Eletronica de Enfermagem
2025
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=192467738&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 192467738 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15181944 1D2L jtl: Revista Eletrônica de Enfermagem issn: 15181944 maglogo: N pubinfo: dt: 2025 vid: 27 pid: 24818 pub: Revista Eletronica de Enfermagem artinfo: ui: 192467738 192467738 192467738 10.5216/ree.v27.76957 192467738 ppf: 1 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Cutaneous reactions caused by injected immunomodulators in the treatment of multiple sclerosis and associated factors. aug: au: de Oliveira, Ligia Nogueira Manso Miot, Hélio Amante Saranholi, Tais Lopes Abbade, Luciana Patrícia Fernandes affil: Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp), Botucatu, São Paulo, Brazil sug: subj: Multiple Sclerosis Drug Therapy Immunologic Factors Administration and Dosage Immunologic Factors Adverse Effects Injections, Subcutaneous Adverse Effects Dermatitis Medicamentosa Risk Factors Drug Hypersensitivity Risk Assessment Brazil Human Male Female Adult Middle Age Descriptive Research Analytic Research Cross Sectional Studies Academic Medical Centers Brazil Nonprobability Sample Convenience Sample Structured Interview Fisher's Exact Test Parametric Statistics Mann-Whitney U Test Kruskal-Wallis Test P-Value T-Tests Data Analysis Software Descriptive Statistics Hyperemia Sclerosis Ecchymosis Edema Depression Obesity Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Objectives: to describe cutaneous reactions caused by injected immunomodulators used for the treatment of multiple sclerosis (MS) and associated factors. Methods: a descriptive and analytical cross-sectional study was conducted with a nonprobability sample of MS patients undergoing treatment at a hospital's neuroimmunology center. The data were collected using structured interviews consisting of two instruments. Results: the sample consisted of 116 MS patients with an average age of 39.8 years, who were predominantly female (72.4%) and white (98.3%). The most prevalent type of MS was relapsing-remitting MS (70.0%). A total of 101 (87.0%) participants developed one or more cutaneous reactions at the injection site. The most frequent reactions were hyperemia (n = 86; 74%), sclerosis (n = 68; 59%), ecchymosis (n = 59; 51%), oedema (n = 53; 46%) and warmth (n = 50; 43%). Reactions were mostly mild and moderate intensity. The factors associated with reactions were depression (p = 0.01) and Body Mass Index considered to be obese (p = 0.04). Conclusions: a significant proportion of patients developed cutaneous reactions at the immunomodulator injection site, and the presence of reactions was associated with depression and obesity. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|