Role of PKM2 Tetramer in Modulating Endothelial Mitochondrial Dysfunction in a Rat Model of Chronic Thromboembolic Pulmonary Hypertension.

Dysfunction of pulmonary artery endothelial cells (PAECs) contributes to the pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH). However, the role of mitochondrial metabolism in this process remains unclear. The present study evaluated whether the tetrameric form of pyruvate kinas...

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Bibliographic Details

Published in:	Physiological Research Vol. 75; no. 1; pp. 45 - 54
Main Authors:	YANG, Min-Xia, WU, Zhi-Zhu, WU, Da-Wen, CHEN, Mao-He, WU, Qiu-Xia, SHAO, Nan, DENG, Chao-Sheng
Format:	Journal Article
Published:	Institute of Physiology, Academy of Sciences of the Czech Republic Feb2026
Online Access:	View this record in EBSCOhost