Role of PKM2 Tetramer in Modulating Endothelial Mitochondrial Dysfunction in a Rat Model of Chronic Thromboembolic Pulmonary Hypertension.

Dysfunction of pulmonary artery endothelial cells (PAECs) contributes to the pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH). However, the role of mitochondrial metabolism in this process remains unclear. The present study evaluated whether the tetrameric form of pyruvate kinas...

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Detalles Bibliográficos
Publicado en:Physiological Research Vol. 75; no. 1; pp. 45 - 54
Autores principales: YANG, Min-Xia, WU, Zhi-Zhu, WU, Da-Wen, CHEN, Mao-He, WU, Qiu-Xia, SHAO, Nan, DENG, Chao-Sheng
Formato: Journal Article
Publicado: Institute of Physiology, Academy of Sciences of the Czech Republic Feb2026
Acceso en línea:Ver este registro en EBSCOhost