Age- and sex-specific muscle health cut-offs improve prognostic accuracy in older patients with heart failure: a secondary analysis of a nationwide, multicenter cohort registry.

Aims Universal muscle health cut-offs for older patients with heart failure often overlook age- and sex-specific biological heterogeneity, potentially compromising prognostic accuracy. We aimed to develop and validate age- and sex-specific cut-off values for muscle health metrics to enhance prognost...

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Bibliographic Details
Published in:	Age & Ageing Vol. 55; no. 2; pp. 1 - 12
Main Authors:	Miki, Yasuhiro, Katano, Satoshi, Nakagama, Takashi, Iwata, Kentaro, Kono, Yuji, Sakurada, Koji, Morisawa, Tomoyuki, Kamiya, Kentaro, Takahashi, Tetsuya
Format:	Article
Published:	Oxford University Press / USA Feb2026
Subjects:	Japan Sex distribution Age distribution Hospital care of older people Old age Hand physiology Mortality risk factors Reference values Risk assessment Predictive tests Skeletal muscle Secondary analysis Data analysis Receiver operating characteristic curves Research evaluation Heart failure Reporting of diseases Longitudinal method Kaplan-Meier estimator Log-rank test Geriatric assessment Research Research methodology Statistics Comparative studies Walking speed Individualized medicine Data analysis software Sarcopenia Sensitivity & specificity (Statistics) Grip strength Proportional hazards models Evaluation
Online Access:	View this record in EBSCOhost