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Polypharmacy, anticholinergic burden and inflammation in relation to accelerated biological ageing.

Background Polypharmacy is an emerging public health issue in ageing populations, linked to various adverse outcomes, yet its effect on biological ageing remains unclear. This study investigated the associations of polypharmacy and anticholinergic burden with biological ageing and evaluated the medi...

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Published in:Age & Ageing Vol. 55; no. 2; pp. 1 - 12
Main Authors: Wei, Kai, Chen, Chun, Sun, Shuimei, Li, Dongmei, Yang, Yanping, Liu, Yan, Zhang, Min, Hu, Kui, Chen, Qi
Format: Article
Published: Oxford University Press / USA Feb2026
Subjects:
Cross-sectional method
Aging
Anthropometry
Old age
Parasympathomimetic agents
Pearson correlation (Statistics)
Research funding
Multiple regression analysis
Polypharmacy
Descriptive statistics
Glucuronidase
Inflammation
Factor analysis
Confidence intervals
Cell receptors
Online Access:View this record in EBSCOhost