Effects of a 24-week resistance exercise program on Alzheimer's disease brain signatures in cognitively unimpaired older adults: a secondary analysis of the AGUEDA randomized controlled trial.

Background Brain imaging markers may help detect early cognitive decline and Alzheimer's disease (AD). Although exercise-related effects on AD-specific brain signatures remain unclear. Objective To examine the effects of a 24-week resistance exercise (RE) program on AD brain signatures in cognitivel...

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Detalles Bibliográficos
Publicado en:	Age & Ageing Vol. 55; no. 4; pp. 1 - 16
Autores principales:	Sanchez-Martinez, Javier, Solis-Urra, Patricio, Fernandez-Gamez, Beatriz, Fernández-Ortega, Javier, Sánchez-Aranda, Lucía, Erickson, Kirk I, Ortega, Francisco B, Esteban-Cornejo, Irene
Formato:	Artículo
Publicado:	Oxford University Press / USA Apr2026
Materias:	Spain Evaluation of human services programs Episodic memory Executive function Aging Psychological tests Exercise physiology Rehabilitation of Alzheimer's patients Alzheimer's disease Secondary analysis Independent living Research funding Cognition disorders in old age Brain Cognitive processing speed Magnetic resonance imaging Descriptive statistics Resistance training Neuroradiology Digital image processing Confidence intervals Factor analysis Data analysis software
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