Sodium Selenite Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension by Upregulating GPX3 and Ameliorating Vascular Remodeling.

Selenium deficiency is implicated in pulmonary arterial hypertension (PAH). This study investigated the effects of sodium selenite (SSE) on PAH and its underlying mechanisms. In a monocrotaline-induced PAH rat model, SSE treatment significantly improved right ventricular systolic pressure (RVSP), me...

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Bibliographic Details

Published in:	Physiological Research Vol. 75; no. 2; pp. 325 - 336
Main Authors:	LIU, Zihua, LIU, Xue, MPRAH, Richard, SUN, Hong, ADU-AMANKWAAH, Joseph, PAN, Xiuhua, CHENG, Shouquan, XIE, Bing, WANG, Cheng, QIAO, Weili
Format:	Journal Article
Published:	Institute of Physiology, Academy of Sciences of the Czech Republic Apr2026
Online Access:	View this record in EBSCOhost