Promoting clinical trials in pediatric IgA nephropathy through extrapolation: an artificial intelligence–enhanced literature review of the disease in pediatrics sponsored by the Kidney Health Initiative.

Background: There is an urgent need to evaluate the efficacy of novel therapeutics that have been approved for use in adults with IgA nephropathy (IgAN) in pediatric patients with this primary glomerular disease. Methods: To explore the feasibility of deploying extrapolation to promote clinical tria...

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Bibliographic Details
Published in:Pediatric Nephrology Vol. 41; no. 8; pp. 2481 - 2488
Main Authors: Selewski, David T., Kerr, Eleanor M., Fajardo, Cecile, Gillespie, Barbara S., Iyer, Sai Prasad N., Khalid, Myda, Komers, Radko, Nakanishi, Koichi, Nelson, Raoul D., Oh, Jun, Schneider, Bonnie, Shah, Lokesh N., Webb, Nicholas J., Zhong, Xuhui, Squillaci, Grace, Lim, Mark D., Trachtman, Howard
Format: review tables/charts Journal Article
Published: Springer Nature Aug2026
Online Access:View this record in EBSCOhost