| Sumario: | Cystic fibrosis (CF) is a multi‐system genetic condition, and CF modulator therapies have transformed health outcomes promising improved longevity. Our aim was to co‐design and implement a nested endocrine and metabolic model of care called CF Endocrine for adults with CF that aligned with consumer and healthcare provider priorities and addressed emerging service gaps in the post‐modulator era. Using mixed‐methods and implementation science methodologies, we designed and conducted surveys, audits and workshops to define service priorities and referral pathways and workflows. In total, 17% of adults attending our CF centre participated in the survey and reported lifestyle optimisation, weight management and diabetes prevention as leading consumer concerns. Four service arms were developed: (i) diabetes support, (ii) bone health, (iii) metabolic health and (iv) reproductive/sexual health. Providers showed strong alignment with consumer priorities and endorsed integration and feasibility of the new nested CF Endocrine service.
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