Assessing the Clinical Relevance of BRCA1 RING Domain Variants of Uncertain Significance.
Simple Summary: Women who inherit harmful variants in the BRCA1 tumour suppressor gene have an elevated risk of developing multiple cancers, and may benefit from increased screening and preventative surgeries. Unfortunately, ~40% of BRCA1 variants have an unknown effect on cancer risk, leaving their...
| Publicado en: | Current Oncology Vol. 33; no. 7; pp. 399 - 424 |
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| Autores principales: | , , , , , |
| Formato: | Journal Article |
| Publicado: |
MDPI
Jul2026
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| Acceso en línea: | Ver este registro en EBSCOhost |