Neuroticism mediates the link of resting-state brain activity and connectivity to subthreshold depression in older women.

Objectives The neurobiology of subthreshold depression, a prevalent and debilitating condition among older women, remains poorly understood. Neuroticism is a known depression risk factor, yet its role in linking brain function to depressive symptoms in this population is understudied. This study inv...

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Detalles Bibliográficos
Publicado en:	Journals of Gerontology Series B: Psychological Sciences & Social Sciences Vol. 81; no. 8; pp. 1 - 12
Autores principales:	Wu, Dongmei, Jiang, Jing, Wang, Song
Formato:	Artículo
Publicado:	Oxford University Press / USA Aug2026
Materias:	China Cross-sectional method Mental health Psychology of women Case-control method Neuroses Mental depression Brain physiology Statistical power analysis Pearson correlation (Statistics) Functional connectivity Research funding Center for Epidemiologic Studies Depression Scale T-test (Statistics) Fisher exact test Prefrontal cortex Magnetic resonance imaging Time series analysis Chi-squared test Descriptive statistics Geriatric Depression Scale Comparative studies Factor analysis Neuroradiology Confidence intervals Data analysis software Nonparametric statistics
Acceso en línea:	Ver este registro en EBSCOhost