Biologic–biologic and biologic–JAK inhibitor combination therapy in refractory systemic autoinflammatory diseases.

Systemic autoinflammatory diseases (SAIDs) arise from genetic defects in innate immunity, leading to dysregulated activation of inflammatory pathways, including interleukin (IL)-1, IL-6, TNF, and JAK/STAT. Clinical manifestations range from recurrent fever to severe complications such as encephaliti...

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Publicado en:	Seminars in Arthritis & Rheumatism Vol. 80
Autores principales:	Tufan, Abdurrahman, Stone, Deborah L., Romeo, Tina, Hoffmann, Patrycja, Wilson, Lorena, Deuitch, Natalie T., Kozycki, Christina, Manthiram, Kalpana, Hansen, Sarah, Kastner, Daniel L., Ombrello, Amanda K.
Formato:	research Journal Article
Publicado:	W B Saunders Oct2026
Acceso en línea:	Ver este registro en EBSCOhost