On the Affinity Regulation of the Metal-Ion-Dependent Adhesion Sites in Integrins.

Density functional theory and a polarizable continuum model are used to (i) understand the affinity modulating mechanisms of the interaction between the metal-ion-dependent adhesion site (MIDAS) of a selected integrin, lymphocyte function-associated antigen-1 (LFA-1) and a ligand mimetic acetate mol...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of the American Chemical Society Vol. 128; no. 11; pp. 3554 - 3564
Autores principales:	San Sebastian, Eider, Mercero, Jose M., Stote, Roland H., Dejaegere, Annick, Cossio, Fernando P., Lopez, Xabier
Formato:	Artículo
Publicado:	American Chemical Society 3/22/2006
Materias:	Integrins Density functionals Metal ions Ligands (Chemistry) Carboxylic acids Adhesion
Acceso en línea:	Ver este registro en EBSCOhost