Chiroptical and Computational Studies of a Bridled Chiroporphyrin and of Its Nickel(II), Copper(II), and Zinc(II) Complexes.

Circular dichroism (CD) spectra and density functional theory (DFT) calculations are reported for a series of conformationally bistable chiroporphyrins with 8-methylene bridles MBCP-8, which can display either an αααα or an αβαβ orientation of their meso substituents. From DFT geometry optimizations...

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Publicado en:Journal of the American Chemical Society Vol. 128; no. 19; pp. 6347 - 6357
Autores principales: Maheut, Geraldine, Castaings, Anna, Pëcaut, Jacques, Daku, Latévi Max Lawson, Pesciteili, Gennaro, Di Bari, Lorenzo, Marchon, Jean-Claude
Formato: Artículo
Publicado: American Chemical Society 5/17/2006
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Acceso en línea:Ver este registro en EBSCOhost
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      pub: American Chemical Society
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        10.1021/ja054926o
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        atl: Chiroptical and Computational Studies of a Bridled Chiroporphyrin and of Its Nickel(II), Copper(II), and Zinc(II) Complexes.
      aug:
        au:
          Maheut, Geraldine
          Castaings, Anna
          Pëcaut, Jacques
          Daku, Latévi Max Lawson
          Pesciteili, Gennaro
          Di Bari, Lorenzo
          Marchon, Jean-Claude
        affil:
          Département de Recherche Fondamentale sur la Matiëre Condensée, CEA-Grenoble
          Département Integration Héterogene Silicium, Leti, CEA-Grenoble
          Université de Genëve
          Dipartimento di Chimica e Chimica industriale, CNR-ICCOM, Via Risorgimento 35, 1-56126 Pisa, Italy
      su:
        Circular dichroism
        Density functionals
        Nickel compounds
        Copper compounds
        Zinc compounds
        Carbenes
      sug:
        subj:
          Circular dichroism
          Density functionals
          Nickel compounds
          Copper compounds
          Zinc compounds
          Carbenes
      ab: Circular dichroism (CD) spectra and density functional theory (DFT) calculations are reported for a series of conformationally bistable chiroporphyrins with 8-methylene bridles MBCP-8, which can display either an αααα or an αβαβ orientation of their meso substituents. From DFT geometry optimizations, the most stable form of ZnBCP-8 is found to be the αααα conformer. By passing to NiBCP-8, there is a strong stabilization of the αβαβ conformation with respect to the αααα conformation, consistent with the X-ray structures of αααα-ZnBCP-8 and αβαβ-NiBCP-8. A correlation between the sign of the CD signal in the Soret region and the conformation of the BCP-8 compounds is reported: the αααα conformers HBCP-8 and ZnBCP-8 show a positive CD signal, whereas the αβαβ conformers NiBCP-8 and CuBCP-8 exhibit a negative signal. The possible contributions to the rotational strengths of αβαβ-NiBCP-8 and αααα-ZnBCP-8, calculated on the basis of their crystal structures, have been analyzed. The CD signals are found to result from a combination of both the inherent chirality of the porphyrin and of extrinsic contributions due to the chiral bridles. These results may have a broad significance for understanding the chiroptical properties of chiral porphyrins and hemoproteins and for monitoring stimuli-responsive, conformationally bistable chiroporphyrin compounds.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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