Fast 2D NMR Ligand Screening Using Hadamard Spectroscopy.
The article focuses on the use of Hadamard encoded spectroscopy for fast two-dimensional nuclear magnetic resonance ligand screening. The applications of Hadamard spectroscopy are discussed. Cross-peaks with selected heteronuclear frequencies are contained in Hadamard encoded HSQC spectra. The use o...
| Publicado en: | Journal of the American Chemical Society Vol. 128; no. 22; pp. 7146 - 7148 |
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| Autores principales: | , , , |
| Formato: | Artículo |
| Publicado: |
American Chemical Society
6/7/2006
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | The article focuses on the use of Hadamard encoded spectroscopy for fast two-dimensional nuclear magnetic resonance ligand screening. The applications of Hadamard spectroscopy are discussed. Cross-peaks with selected heteronuclear frequencies are contained in Hadamard encoded HSQC spectra. The use of selective pulses that would cause sensitivity losses for large proteins is a possible limitation of Hadamard encoded heterocorrelation spectra. |
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