Generation and Reactions of o-Bromophenyllithium without Benzyne Formation Using a Microreactor.

The article examines the reaction of o-Bromophenyllithium without benzyne formation using a microreactor. It is noted that an efficient way of controlling the generations and reactions of highly reactive intermediates can be accomplished by virtue of precise residence time control and temperature co...

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Publicado en:Journal of the American Chemical Society Vol. 129; no. 11; pp. 3046 - 3048
Autores principales: Usutani, Hirotsugu, Tomida, Yutaka, Nagaki, Aiichiro, Okamoto, Hideho, Nokami, Toshiki, Yoshida, Jun-ichi
Formato: Artículo
Publicado: American Chemical Society 3/21/2007
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Generation and Reactions of o-Bromophenyllithium without Benzyne Formation Using a Microreactor.
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          Usutani, Hirotsugu
          Tomida, Yutaka
          Nagaki, Aiichiro
          Okamoto, Hideho
          Nokami, Toshiki
          Yoshida, Jun-ichi
        affil: Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan
      su:
        Intermediates (Chemistry)
        Microreactors
        Temperature control
        Lithium
        Temperature
      sug:
        subj:
          Intermediates (Chemistry)
          Microreactors
          Temperature control
          Lithium
          Temperature
      ab: The article examines the reaction of o-Bromophenyllithium without benzyne formation using a microreactor. It is noted that an efficient way of controlling the generations and reactions of highly reactive intermediates can be accomplished by virtue of precise residence time control and temperature control inherent in microsystems. The microflow systems server as a powerful tool for mechanistic studies on reactions involving highly unstable intermediates such as o-bromophenyllithium.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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