Kinetics studies on triacontanyl palmitate: a urease inhibitor.
The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive in...
| Publicado en: | Natural Product Research Vol. 21; no. 8; pp. 721 - 726 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jul2007
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| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these enzymes. Ki values were found to be 60.03 ± 1.72 and 88.23 ± 0.31 µM against jack bean and B. pasteurii ureases, respectively. |
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