Kinetics studies on triacontanyl palmitate: a urease inhibitor.
The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive in...
| Publicado en: | Natural Product Research Vol. 21; no. 8; pp. 721 - 726 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jul2007
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=25729679&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 25729679 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14786419 RFT jtl: Natural Product Research issn: 14786419 maglogo: Y pubinfo: dt: Jul2007 vid: 21 iid: 8 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 25729679 25729679 10.1080/14786410600906913 25729679 ppf: 721 ppct: 5 formats: tig: atl: Kinetics studies on triacontanyl palmitate: a urease inhibitor. aug: au: Lodhi, Muhammad Arif Abbasi, Muhammad Athar Choudhary*, Muhammad Iqbal Ahmad, Viqar Uddin affil: Dr Panjwani Center for Molecular Medicine and Drug Research, HEJ Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan sug: ab: The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these enzymes. Ki values were found to be 60.03 ± 1.72 and 88.23 ± 0.31 µM against jack bean and B. pasteurii ureases, respectively. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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