Aptamer-Based Optical Probes with Separated Molecular Recognition and Signal Transduction Modules.

The article discusses aptamers being nucleic acids that can attach to a great variety of molecular targets. It is suggested that extensive efforts have been exhausted on acquiring aptamer-based optical sensors. It is inferred that slight modifications on aptamers may contribute to substantial loss i...

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Detalles Bibliográficos
Publicado en:Journal of the American Chemical Society Vol. 130; no. 8; pp. 2380 - 2382
Autores principales: Na Li, Chih-ming Ho
Formato: Artículo
Publicado: American Chemical Society 2/27/2008
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Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:The article discusses aptamers being nucleic acids that can attach to a great variety of molecular targets. It is suggested that extensive efforts have been exhausted on acquiring aptamer-based optical sensors. It is inferred that slight modifications on aptamers may contribute to substantial loss in their affinity and specificity.