Aptamer-Based Optical Probes with Separated Molecular Recognition and Signal Transduction Modules.

The article discusses aptamers being nucleic acids that can attach to a great variety of molecular targets. It is suggested that extensive efforts have been exhausted on acquiring aptamer-based optical sensors. It is inferred that slight modifications on aptamers may contribute to substantial loss i...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of the American Chemical Society Vol. 130; no. 8; pp. 2380 - 2382
Autores principales: Na Li, Chih-ming Ho
Formato: Artículo
Publicado: American Chemical Society 2/27/2008
Materias:
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=31156140&site=ehost-live
header:
  @attributes:
    shortDbName: hlh
    uiTerm: 31156140
    longDbName: Humanities International Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    jinfo:
      jid:
        00027863
        ACS
      jtl: Journal of the American Chemical Society
      issn: 00027863
      maglogo: N
    pubinfo:
      dt: 2/27/2008
      vid: 130
      iid: 8
      pid: 997
      pub: American Chemical Society
    artinfo:
      ui:
        31156140
        10.1021/ja076787b
      ppf: 2380
      ppct: 2
      formats:
      tig:
        atl: Aptamer-Based Optical Probes with Separated Molecular Recognition and Signal Transduction Modules.
      aug:
        au:
          Na Li
          Chih-ming Ho
        affil: Center for Cell Control and Department of Mechanical and Aerospace Engineering, Henry Samueli School of Engineering and Applied Science, University of California, Los Angeles, Los Angeles, California 90095
      su:
        Genetic transformation
        Microbial genetics
        Microbial mutation
        Biosensor industry
        Viral genetics
        Structural optimization
      sug:
        subj:
          Genetic transformation
          Microbial genetics
          Microbial mutation
          Biosensor industry
          Viral genetics
          Structural optimization
      ab: The article discusses aptamers being nucleic acids that can attach to a great variety of molecular targets. It is suggested that extensive efforts have been exhausted on acquiring aptamer-based optical sensors. It is inferred that slight modifications on aptamers may contribute to substantial loss in their affinity and specificity.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
    refInfo:
    copyright:
      @attributes:
        flag: Y
      dt:
        @attributes:
          year: 2008
    holdings:
      @attributes:
        islocal: N