Computational Study of Thymine Dimer Radical Anion Splitting in the Self-Repair Process of Duplex DNA.

Formation of the thymine dimer is one of the most important types of photochemical damage in DNA, responsible for several biological pathologies. Though specifically designed proteins (photolyases) can efficiently repair this type of damage in living cells, an autocatalytic activity of the DNA itsel...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of the American Chemical Society Vol. 130; no. 11; pp. 3443 - 3451
Autores principales:	Masson, Fanny, Laino, Teodoro, Tavernelli, Ivano, Rothlisberger, Ursula, Hutter, Jürg
Formato:	Artículo
Publicado:	American Chemical Society 3/19/2008
Materias:	Thymine DNA Proteins Density functionals Molecular dynamics Functional analysis
Acceso en línea:	Ver este registro en EBSCOhost