Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents.

The article reports on the study of the synthesis of fluorine-18 nanoparticles as vivo molecular imaging agents. It aims to examine the limits of enhanced permeability and retention effect (EPR effect) and to determine the possible nanoparticle size for tumor targeting. It also uses the ring opening...

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Publicado en:Journal of the American Chemical Society Vol. 130; no. 21; pp. 6731 - 6734
Autores principales: Matson, John B., Grubbs, Robert H.
Formato: Artículo
Publicado: American Chemical Society 5/28/2008
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents.
      aug:
        au:
          Matson, John B.
          Grubbs, Robert H.
        affil: NanoSystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, MC 12 7-72, California Institute of Technology, Pasadena, California 91125
      su:
        Fluorine
        Nanoparticles
        Imaging systems
        Polymerization
        Ring-opening polymerization
        Chemical reactions
      sug:
        subj:
          Fluorine
          Nanoparticles
          Imaging systems
          Polymerization
          Ring-opening polymerization
          Chemical reactions
      ab: The article reports on the study of the synthesis of fluorine-18 nanoparticles as vivo molecular imaging agents. It aims to examine the limits of enhanced permeability and retention effect (EPR effect) and to determine the possible nanoparticle size for tumor targeting. It also uses the ring opening metathesis polymerization (ROMP) to produce low polydispersity amphiphilic block copolymers of the cinnamoyl group.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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