Nitrosyl Derivatives of Diiron(I) Dithiolates Mimic the Structure and Lewis Acidity of the [FeFe]-Hydrogenase Active Site.

This study probes the impact of electronic asymmetry of diiron(l) dithiolato carbonyls. Treatment of Fe(SCH)(CO)(PMe) compounds (n = 2, 3; x = 1, 2, 3) with NOBF gave the derivatives [Fe(SCH)(CO)(PMe)(NO)]BF, which are electronically unsymmetrical because of the presence of a single NO ligand. Where...

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Publicado en:Journal of the American Chemical Society Vol. 130; no. 36; pp. 12021 - 12031
Autores principales: Olsen, Matthew T., Bruschi, Maurizio, De Gioia, Luca, Rauchfuss, Thomas B., Wilson, Scott A.
Formato: Artículo
Publicado: American Chemical Society 9/10/2008
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: 9/10/2008
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      pub: American Chemical Society
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        10.1021/ja802268p
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        atl: Nitrosyl Derivatives of Diiron(I) Dithiolates Mimic the Structure and Lewis Acidity of the [FeFe]-Hydrogenase Active Site.
      aug:
        au:
          Olsen, Matthew T.
          Bruschi, Maurizio
          De Gioia, Luca
          Rauchfuss, Thomas B.
          Wilson, Scott A.
        affil:
          Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801
          Department of Biotechnology and Biosciences, University of Milano—Bicocca, Piazza della Scienza 1, 20126 Milan, Italy
      su:
        Organoiron compounds
        Density functionals
        Enantiomers
        Electrons
        Electrophiles
      sug:
        subj:
          Organoiron compounds
          Density functionals
          Enantiomers
          Electrons
          Electrophiles
      ab: This study probes the impact of electronic asymmetry of diiron(l) dithiolato carbonyls. Treatment of Fe(SCH)(CO)(PMe) compounds (n = 2, 3; x = 1, 2, 3) with NOBF gave the derivatives [Fe(SCH)(CO)(PMe)(NO)]BF, which are electronically unsymmetrical because of the presence of a single NO ligand. Whereas the monophosphine derivative is largely undistorted, the bis(PMe) derivatives are distorted such that the CO ligand on the Fe(CO)(PMe)(NO) subunit is semibridging. Two isomers of [Fe(SCH)(CO)(PMe)(NO)]BF were characterized spectroscopically and crystallographically. Each isomer features electron-rich Fe(CO)PMe and electrophilic Fe(CO)(PMe)(NO) subunits. These species are in equilibrium with an unobserved isomer that reversibly binds CO (ΔH = -35 kJ/mol, ΔS = -139 J mol K) to give the symmetrical adduct [Fe(SCH)(μ-NO)(CO)(PMe)]BF. In contrast to Fe(SCH)(CO)(PMe), the bis(PMe) nitrosyl complexes readily undergo CO substitution to give the (PMe) derivatives. The nitrosyl complexes reduce at potentials that are ~1 V milder than their carbonyl counterparts. Results of density functional theory calculations, specifically natural bond orbital analysis, reinforce the electronic resemblance of the nitrosyl complexes to the corresponding mixed-valence diiron complexes. Unlike other diiron dithiolato carbonyls, these species undergo reversible reductions at mild potentials. The results show that the novel structural and chemical features associated with mixed-valence diiron dithiolates (the so-called H models) can be replicated in the absence of mixed-valency by the introduction of electronic asymmetry.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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          year: 2008
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