Introduction of Cationic Charge into DNA Near the Major Groove Edge of a Guanine•Cytosine Base Pair: Characterization of Oligodeoxynucleotides Substituted with 7-Aminomethyl-7-deaza-2′-deoxyguanosine.
The article presents a study on the synthesis of 7-aminomethyl-7-deaza-dG in the creation of a structural model of groove associated cations. The structural model has been used to be able to reflect cation distribution and location which has been observed in DNA structures. The study reveals its fin...
| Publicado en: | Journal of the American Chemical Society Vol. 131; no. 34; pp. 12068 - 12070 |
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| Autores principales: | , , , |
| Formato: | Artículo |
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American Chemical Society
9/2/2009
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=44230166&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 44230166 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00027863 ACS jtl: Journal of the American Chemical Society issn: 00027863 maglogo: N pubinfo: dt: 9/2/2009 vid: 131 iid: 34 pid: 997 pub: American Chemical Society artinfo: ui: 44230166 10.1021/ja904930p ppf: 12068 ppct: 2 formats: tig: atl: Introduction of Cationic Charge into DNA Near the Major Groove Edge of a Guanine•Cytosine Base Pair: Characterization of Oligodeoxynucleotides Substituted with 7-Aminomethyl-7-deaza-2′-deoxyguanosine. aug: au: Ganguly, Manjori Ruo-Wen Wang Marky, Luis A. Gold, Barry affil: University of Pittsburgh, Department of Pharmaceutical Sciences, 3501 Terrace Street, Pittsburgh, Pennsylvania 15261 University of Nebraska Medical Center, Department of Pharmaceutical Sciences, Omaha, Nebraska 68198-6025 su: Structural frame models Cations DNA Spectrum analysis Thermodynamics sug: subj: Structural frame models Cations DNA Spectrum analysis Thermodynamics ab: The article presents a study on the synthesis of 7-aminomethyl-7-deaza-dG in the creation of a structural model of groove associated cations. The structural model has been used to be able to reflect cation distribution and location which has been observed in DNA structures. The study reveals its findings on the spectroscopic and thermodynamic characterization of DNA. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y dt: @attributes: year: 2009 holdings: @attributes: islocal: N |
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