Mechanism of Glycan Receptor Recognition and Specificity Switch for Avian, Swine, and Human Adapted Influenza Virus Hemagglutinins: A Molecular Dynamics Perspective.

Hemagglutinins (HA's) from duck, swine, and human influenza viruses have previously been shown to prefer avian and human glycan receptor analogues with distinct topological profiles, pentasaccharides LSTa (α-2,3 linkage) and LSTc (α-2,6 linkage), in comparative molecular dynamics studies. On the bas...

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Publicado en:	Journal of the American Chemical Society Vol. 131; no. 47; pp. 17430 - 17443
Autores principales:	Newhouse, E. Irene, Dong Xu, Markwick, Phineus R. L., Amaro, Rommie E., Pao, Hsing C., Wu, Kevin J., Alam, Maqsudul, McCammon, J. Andrew, Li, Wilfred W.
Formato:	Artículo
Publicado:	American Chemical Society 12/2/2009
Materias:	Influenza Respiratory infections Hemagglutinin Immunity Blood agglutination Preventive medicine
Acceso en línea:	Ver este registro en EBSCOhost