All-trans retinoid acid increases Notch1 transcript expression in acute promyelocytic leukemia.

The effect of all-trans retinoid acid (ATRA) on the expression of Notch1 gene by real-time reverse transcriptase polymerase chain reaction (RT-PCR) in acute promyelocytic leukemia cells (APL), NB4, and HL-60 lacking t(15;17) was studied. The cells were treated with ATRA 0.5 microM for up to 96 hours...

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Bibliographic Details
Published in:Advances in Therapy Vol. 20; no. 6; pp. 337 - 344
Main Authors: Lin, Jen-Tsun, Wu, Ming-Shiuan, Wang, Wei-Shu, Yen, Chueh-Chuan, Chiou, Tzeon-Jye, Liu, Jin-Hwang, Yang, Mu-Hua, Chao, Ta-Chon, Chou, Shu-Chaou, Chen, Po-Min
Format: research Journal Article
Published: Springer Nature Nov2003
Online Access:View this record in EBSCOhost