Septal Infusions of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel (HCN-Channel) Blocker ZD7288 Impair Spontaneous Alternation But Not Inhibitory Avoidance.

Blockade of septal hyperpolarization-activated cyclic nucleotide-gated channels (HCN) impairs hippocampal theta, an effect that would be expected to impair memory. To test this hypothesis, the present experiments determined whether septal infusions of the selective HCN channel blocker ZD7288 would i...

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Detalles Bibliográficos

Publicado en:	Behavioral Neuroscience Vol. 122; no. 3; pp. 549 - 557
Autores principales:	Cissé, Ramata S., Krebs-Kraft, Desiree L., Parent, Marise B.
Formato:	Artículo
Publicado:	American Psychological Association June 2008
Materias:	Ion channels Laboratory rats Animal memory Brain function localization
Acceso en línea:	Ver este registro en EBSCOhost