How frailty models can be used for evaluating longevity limits: taking advantage of an interdisciplinary approach.

Part of a special issue on the demography of aging. The writers consider an approach to the examination of mortality and longevity limits when survival data on related individuals with and without observed covariates are present. They maintain that the method blends the concepts of demography and...

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Publicado en:Demography Vol. 34; pp. 31 - 49
Autores principales: Yashin, Anatoli I., Iachine, Ivan A.
Formato: Artículo
Publicado: Springer Science & Business Media B.V. February 1997
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Science & Business Media B.V.
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        atl: How frailty models can be used for evaluating longevity limits: taking advantage of an interdisciplinary approach.
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          Yashin, Anatoli I.
          Iachine, Ivan A.
      su:
        Interdisciplinary research
        Mortality -- Mathematical models
        Longevity
        Mathematical models
        Genetics of aging
        Twins
        Statistics
        Demography methodology
      sug:
        subj:
          Interdisciplinary research
          Mortality -- Mathematical models
          Longevity
          Mathematical models
          Genetics of aging
          Twins
          Statistics
          Demography methodology
      ab: Part of a special issue on the demography of aging. The writers consider an approach to the examination of mortality and longevity limits when survival data on related individuals with and without observed covariates are present. They maintain that the method blends the concepts of demography and survival analysis with methods of quantitative genetics and genetic epidemiology and that it permits them to examine the genetic structure of frailty in the Cox-type hazard model with random effects. They describe the application of this approach to survival data on Danish twins, and they then assess the resulting lower bounds for biological limits of human longevity. Finally, they consider the limitations of this approach and outline directions for additional research.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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