Molecular Complexity via C-H Activation: A Dehydrogenative Diels-Alder Reaction.
Traditionally, C-H oxidation reactions install oxidized functionality onto a preformed molecular skeleton, resulting in a local molecular change. The use of C-H activation chemistry to construct complex molecular scaffolds is a new area with tremendous potential in synthesis. We report a Pd(II)/bis-...
| Publicado en: | Journal of the American Chemical Society Vol. 133; no. 38; pp. 14892 - 14896 |
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| Autores principales: | , |
| Formato: | Artículo |
| Publicado: |
American Chemical Society
9/28/2011
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | Traditionally, C-H oxidation reactions install oxidized functionality onto a preformed molecular skeleton, resulting in a local molecular change. The use of C-H activation chemistry to construct complex molecular scaffolds is a new area with tremendous potential in synthesis. We report a Pd(II)/bis-sulfoxide-catalyzed dehydrogenative Diels-Alder reaction that converts simple terminal olefins into complex cycloadducts in a single operation. |
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