Sampling--The "Mother Lode" of All Errors.

Before analytical error can be reduced, it must be understood. This means being able to separate assay and sampling error. A hierarchical study is an effective way to separate assay, sampling, and process errors. A hierarchical study retains the time order sequence of the data, making process invest...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Validation Technology (JVT) Vol. 18; no. 1; pp. 45 - 50
Autores principales: McConnell, John, Nunnally, Brian, McGarvey, Bernard
Formato: equations & formulas tables/charts Journal Article
Publicado: Institute of Validation Technology Winter2012
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Before analytical error can be reduced, it must be understood. This means being able to separate assay and sampling error. A hierarchical study is an effective way to separate assay, sampling, and process errors. A hierarchical study retains the time order sequence of the data, making process investigation and improvement simpler. The best estimates for analytical error are produced by blind controls. A hierarchical study can provide an effective de facto blind control.