Sampling--The "Mother Lode" of All Errors.
Before analytical error can be reduced, it must be understood. This means being able to separate assay and sampling error. A hierarchical study is an effective way to separate assay, sampling, and process errors. A hierarchical study retains the time order sequence of the data, making process invest...
| Published in: | Journal of Validation Technology (JVT) Vol. 18; no. 1; pp. 45 - 50 |
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| Main Authors: | , , |
| Format: | equations & formulas tables/charts Journal Article |
| Published: |
Institute of Validation Technology
Winter2012
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| Online Access: | View this record in EBSCOhost |
| Summary: | Before analytical error can be reduced, it must be understood. This means being able to separate assay and sampling error. A hierarchical study is an effective way to separate assay, sampling, and process errors. A hierarchical study retains the time order sequence of the data, making process investigation and improvement simpler. The best estimates for analytical error are produced by blind controls. A hierarchical study can provide an effective de facto blind control. |
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