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Development of NIR Fluorescent Dyes Based on Si-rhodamine for in Vivo Imaging.

We have developed a series of novel near-infrared (NIR) wavelength-excitable fluorescent dyes, SiR-NIRs, by modifying the Si—rhodamine scaffold to obtain emission in the range suitable for in vivo imaging. Among them, SiR680 and SiR700 showed sufficiently high quantum efficiency in aqueous media. Bo...

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Published in:Journal of the American Chemical Society Vol. 134; no. 11; pp. 5029 - 5032
Main Authors: Koide, Yuichiro, Urano, Yasuteru, Hanaoka, Kenjiro, Wen Piao, Kusakabe, Moriaki, Saito, Nae, Terai, Takuya, Okabe, Takayoshi, Nagano, Tetsuo
Format: Article
Published: American Chemical Society 3/21/2012
Subjects:
Fluorescent dyes
Chemical structure
Fluorescent dyes spectra
Silicon compounds
Rhodamines
Imaging systems
Fluorescent probes
Online Access:View this record in EBSCOhost