Mechanism and Stereoselectivity of a Dual Amino-Catalyzed Robinson Annulation: Rare Duumvirate Stereocontrol.

Computational study of the mechanisms and stereoselectivities of a dual amino-catalyzed synthesis of cyclohexenones containing all-carbon α-quaternary and ∂-tertiary stereocenters is reported. Extensive conformational search with density functional theory optimizations, the high-accuracy SCS-MP2/cc-...

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Publicado en:	Journal of the American Chemical Society Vol. 134; no. 33; pp. 13624 - 13632
Autores principales:	Pierce, Matthew D., Johnston, Ryne C., Mahapatra, Subham, Hua Yang, Carter, Rich G., Cheong, Paul Ha-Yeon
Formato:	Artículo
Publicado:	American Chemical Society 8/22/2012
Materias:	Cyclohexenones Density functionals Solvation Amines Aldehydes
Acceso en línea:	Ver este registro en EBSCOhost