Electronic Measurements of Single-Molecule Processing by DNA Polymerase I (Klenow Fragment).

Bioconjugating single molecules of the Klenow fragment of DNA polymerase I into electronic nanocircuits allowed electrical recordings of enzymatic function and dynamic variability with the resolution of individual nucleotide incorporation events. Continuous recordings of DNA polymerase processing mu...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of the American Chemical Society Vol. 135; no. 21; pp. 7855 - 7861
Autores principales:	Olsen, Tivoli J., Yongki Choi, Sims, Patrick C., Tolga Gul, O., Corso, Brad L., Chengjun Dong, Brown, William A., Collins, Philip G., Weiss, Gregory A.
Formato:	Artículo
Publicado:	American Chemical Society 5/29/2013
Materias:	DNA polymerases kinetics Single molecule research Biochemical templates Bioconjugates Electronic measurements Nucleotides Phosphodiesters
Acceso en línea:	Ver este registro en EBSCOhost