Phosphoryl Transfers of the Phospholipase D Superfamily: A Quantum Mechanical Theoretical Study.

The HKD-containing Phospholipase D superfamily catalyzes the cleavage of the headgroup of phosphatidylcholine to produce phosphatidic acid and choline. The mechanism of this cleavage process is studied theoretically. The geometric basis of our models is the X-ray crystal structure of the five-coordi...

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Detalles Bibliográficos
Publicado en:Journal of the American Chemical Society Vol. 135; no. 37; pp. 13764 - 13775
Autores principales: DeYonker, Nathan J., Webster, Charles Edwin
Formato: Artículo
Publicado: American Chemical Society 9/18/2013
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Acceso en línea:Ver este registro en EBSCOhost