Coinage-Metal Mediated Ring Opening of cis-1,2-Dimethoxycyclopropane: Trends from the Gold, Copper, and Silver Fischer Carbene Bond Strength.

N-heterocyclic carbene (NHC) supported coinage metal cations proved to react in the gas phase with the electron-rich cis-l,2-dimethoxycydopropane. Upon Collision Induced Dissociation (CID), several spectrometric fragment-ion signals were observed, one corresponding to the recovery of the bare cation...

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Publicado en:Journal of the American Chemical Society Vol. 136; no. 26; pp. 9296 - 9308
Autores principales: Batiste, Laurent, Chen, Peter
Formato: Artículo
Publicado: American Chemical Society 7/2/2014
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/2/2014
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      pub: American Chemical Society
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        10.1021/ja4084495
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        atl: Coinage-Metal Mediated Ring Opening of cis-1,2-Dimethoxycyclopropane: Trends from the Gold, Copper, and Silver Fischer Carbene Bond Strength.
      aug:
        au:
          Batiste, Laurent
          Chen, Peter
        affil: Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule (ETH Zürich), Vladimir-Prelog-Strasse 2, CH-8093 Zürich, Switzerland
      su:
        Carbenes
        Bond strengths
        Heterocyclic compounds
        Cations
        Gas phase reactions
        Density functional theory
        Dissociation (Chemistry)
        Moieties (Chemistry)
      sug:
        subj:
          Carbenes
          Bond strengths
          Heterocyclic compounds
          Cations
          Gas phase reactions
          Density functional theory
          Dissociation (Chemistry)
          Moieties (Chemistry)
      ab: N-heterocyclic carbene (NHC) supported coinage metal cations proved to react in the gas phase with the electron-rich cis-l,2-dimethoxycydopropane. Upon Collision Induced Dissociation (CID), several spectrometric fragment-ion signals were observed, one corresponding to the recovery of the bare cation IMes-M (IMes = l,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene) and the second to the methoxymethylidene metal complex IMes—M—[HCOCH3]. The gold and copper complexes appear to stabilize the carbene sufficiently enough to promote the latter channel. On the contrary, the silver complex binds weakly to the methoxymethylidene moiety as observed by the predominance of the bare cation IMes—M channel. Density Functional Theory (DFT) investigations of the Potential Energy Surface and Bond Energy Decomposition Analyses provided results that correlate well with the experimental data. In the case of the bare cation channel, two distinct reaction pathways were found: a straightforward decoordination of the cyclopropane and a cationic rearrangement of the three-membered ring into a dimethoxypropylene isomer before dissociation. However, for the abstraction of the methoxymethylidene moiety by the metal cation, only one pathway was found. In analogy to earlier studies by other groups, we found the trend Au > Cu > Ag for the metal—carbene bond strength.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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