Emerging Therapeutic Options for Eosinophilic Esophagitis.

Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus that often occurs in atopic persons. Management strategies include pharmacotherapy, dietary modification, and endoscopic therapy, although patients will often have a relapsing and remitting course. Currently, the pri...

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Detalles Bibliográficos
Publicado en:Gastroenterology & Hepatology Vol. 10; no. 2; pp. 106 - 117
Autores principales: Dougherty Jr., Timothy, Stephen, Sindu, Borum, Marie L., Doman, David B.
Formato: pictorial tables/charts Journal Article
Publicado: Gastro-Hep Communications, Inc Feb2014
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus that often occurs in atopic persons. Management strategies include pharmacotherapy, dietary modification, and endoscopic therapy, although patients will often have a relapsing and remitting course. Currently, the primary pharmacotherapy for EoE consists of corticosteroids. Immunomodulators, leukotriene antagonists, biologics, and monoclonal antibodies are currently under study for treatment of EoE. The role of immunoglobulin E–mediated allergic reactions has been well documented and may provide insight into the etiology and effective therapy of EoE.