The Chemopreventive Effect of the Dietary Compound Kaempferol on the MCF-7 Human Breast Cancer Cell Line Is Dependent on Inhibition of Glucose Cellular Uptake.

Our aim was to investigate the effect of several dietary polyphenols on glucose uptake by breast cancer cells. Uptake of3H-deoxy-D-glucose (3H-DG) by MCF-7 cells was time-dependent, saturable, and inhibited by cytochalasin B plus phloridzin. In the short-term (26 min), myricetin, chrysin, genistein,...

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Publicado en:Nutrition & Cancer Vol. 67; no. 3; pp. 504 - 514
Autores principales: Azevedo, Cláudia, Correia-Branco, Ana, Araújo, João R., Guimarães, João T., Keating, Elisa, Martel, Fátima
Formato: equations & formulas research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Apr2015
Acceso en línea:Ver este registro en EBSCOhost