The Chemopreventive Effect of the Dietary Compound Kaempferol on the MCF-7 Human Breast Cancer Cell Line Is Dependent on Inhibition of Glucose Cellular Uptake.

Our aim was to investigate the effect of several dietary polyphenols on glucose uptake by breast cancer cells. Uptake of3H-deoxy-D-glucose (3H-DG) by MCF-7 cells was time-dependent, saturable, and inhibited by cytochalasin B plus phloridzin. In the short-term (26 min), myricetin, chrysin, genistein,...

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Bibliographic Details
Published in:Nutrition & Cancer Vol. 67; no. 3; pp. 504 - 514
Main Authors: Azevedo, Cláudia, Correia-Branco, Ana, Araújo, João R., Guimarães, João T., Keating, Elisa, Martel, Fátima
Format: equations & formulas research tables/charts Journal Article
Published: Taylor & Francis Ltd Apr2015
Online Access:View this record in EBSCOhost