Microsatellite Instability in Sarcoma: Fact or Fiction?

Microsatellite instability (MSI) is a unique molecular abnormality, indicative of a deficient DNA mismatch repair (MMR) system. Described and characterized in the colorectal cancer literature, the MSI-positive phenotype is predictive of disease susceptibility, pathogenesis, and prognosis. The clinic...

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Bibliographic Details

Published in:	ISRN Oncology pp. 1 - 10
Main Authors:	Monument, Michael J., Lessnick, Stephen L., Schiffman, Joshua D., Randall, Rl. Tx.
Format:	equations & formulas historical material pictorial review tables/charts Journal Article
Published:	Wiley-Blackwell 2012
Online Access:	View this record in EBSCOhost