Microsatellite Instability in Sarcoma: Fact or Fiction?

Microsatellite instability (MSI) is a unique molecular abnormality, indicative of a deficient DNA mismatch repair (MMR) system. Described and characterized in the colorectal cancer literature, the MSI-positive phenotype is predictive of disease susceptibility, pathogenesis, and prognosis. The clinic...

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Detalles Bibliográficos
Publicado en:ISRN Oncology pp. 1 - 10
Autores principales: Monument, Michael J., Lessnick, Stephen L., Schiffman, Joshua D., Randall, Rl. Tx.
Formato: equations & formulas historical material pictorial review tables/charts Journal Article
Publicado: Wiley-Blackwell 2012
Acceso en línea:Ver este registro en EBSCOhost