Adverse reactions to the sulphite additives.

Sulphites are widely used as preservative and antioxidant additives in the food and pharmaceutical industries. Exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals¡ ranging from dermatitis¡ urticaria¡ flushing¡ hypotension¡ abdominal pain and...

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Publicado en:Gastroenterology & Hepatology from Bed to Bench Vol. 5; no. 1; pp. 16 - 24
Autores principales: Vally, H, Misso, NLA
Formato: review tables/charts Journal Article
Publicado: Gastroenterology & Hepatology from Bed to Bench Jan2012
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Adverse reactions to the sulphite additives.
      aug:
        au:
          Vally, H
          Misso, NLA
      sug:
        subj:
          Adverse Health Care Event Prevention and Control
          Sulfites Adverse Effects
          Asthma Risk Factors
          Disinfectants
          Food
          Food Hypersensitivity Diagnosis
          Gastroenterology Care
          Occupational Hazards Prevention and Control
          Sulfites Therapeutic Use
      ab: Sulphites are widely used as preservative and antioxidant additives in the food and pharmaceutical industries. Exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals¡ ranging from dermatitis¡ urticaria¡ flushing¡ hypotension¡ abdominal pain and diarrhoea to life-threatening anaphylactic and asthmatic reactions. Exposure to the sulphites arises mainly from the consumption of foods and drinks that contain these additives; however exposure may also occur through the use of pharmaceutical products¡ as well as in occupational settings. Most studies report a prevalence of sulphite sensitivity of 3 to 10% among asthmatic subjects who ingest these additives. However¡ the severity of these reactions varies¡ and steroid-dependent asthmatics¡ those with marked airway hyperresponsiveness¡ and children with chronic asthma¡ appear to be at greater risk. Although a number of potential mechanisms have been proposed¡ the precise mechanisms underlying sulphite sensitivity remain unclear.
      pubtype: Academic Journal
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        tables/charts
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    language: English
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