Adverse reactions to the sulphite additives.
Sulphites are widely used as preservative and antioxidant additives in the food and pharmaceutical industries. Exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals¡ ranging from dermatitis¡ urticaria¡ flushing¡ hypotension¡ abdominal pain and...
| Publicado en: | Gastroenterology & Hepatology from Bed to Bench Vol. 5; no. 1; pp. 16 - 24 |
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| Autores principales: | , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
Gastroenterology & Hepatology from Bed to Bench
Jan2012
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| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | Sulphites are widely used as preservative and antioxidant additives in the food and pharmaceutical industries. Exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals¡ ranging from dermatitis¡ urticaria¡ flushing¡ hypotension¡ abdominal pain and diarrhoea to life-threatening anaphylactic and asthmatic reactions. Exposure to the sulphites arises mainly from the consumption of foods and drinks that contain these additives; however exposure may also occur through the use of pharmaceutical products¡ as well as in occupational settings. Most studies report a prevalence of sulphite sensitivity of 3 to 10% among asthmatic subjects who ingest these additives. However¡ the severity of these reactions varies¡ and steroid-dependent asthmatics¡ those with marked airway hyperresponsiveness¡ and children with chronic asthma¡ appear to be at greater risk. Although a number of potential mechanisms have been proposed¡ the precise mechanisms underlying sulphite sensitivity remain unclear. |
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