Effects of fatty and lean fish intake on blood pressure in subjects with coronary heart disease using multiple medications.
Background: Intake of fish and long-chain n-3 fatty acids has been of wide interest due to their beneficial effects on cardiovascular risk factors and lower coronary heart disease (CHD) risk. Aim of the study: The aim of this pilot study was to examine the effects of fatty fish and lean (white) fish...
| Publicado en: | European Journal of Nutrition Vol. 47; no. 6; pp. 319 - 329 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Sep2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105687545&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105687545 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Sep2008 vid: 47 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 105687545 2010019263 10.1007/s00394-008-0728-5 NLM18665413 105687545 ppf: 319 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Effects of fatty and lean fish intake on blood pressure in subjects with coronary heart disease using multiple medications. aug: au: Erkkilä AT Schwab US de Mello VDF Lappalainen T Mussalo H Lehto S Kemi V Lamberg-Allardt C Uusitupa MIJ affil: Department of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland sug: subj: Blood Pressure Cardiovascular Risk Factors Coronary Disease Drugs, Prescription Fish Metabolism Fish Physiology Lipids Aged Analysis of Variance Apolipoproteins Chi Square Test Docosahexaenoic Acids Eicosapentaenoic Acid Female Finland Funding Source Heart Rate Lipoproteins, HDL Cholesterol Male Middle Age Myocardial Infarction Myocardial Ischemia Pilot Studies Post Hoc Analysis T-Tests Triglycerides Vitamin D Human Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Background: Intake of fish and long-chain n-3 fatty acids has been of wide interest due to their beneficial effects on cardiovascular risk factors and lower coronary heart disease (CHD) risk. Aim of the study: The aim of this pilot study was to examine the effects of fatty fish and lean (white) fish on fatty acid composition of serum lipids and cardiovascular risk factors in subjects with CHD using multiple drugs for this condition. Methods: The study was an 8-week controlled, parallel intervention. Inclusion criteria were myocardial infarction or unstable ischemic attack, age under 70 years, use of betablockers and presence of sinus rhythm. The subjects were randomized to one of the following groups: 4 meals/week fatty fish (n = 11), 4 meals/week lean fish (n = 12) and control diet including lean meat (n = 10). Results: The mean (+/-SD) of reported fish meals per week was 4.3 +/- 0.4, 4.7 +/- 1.1 and 0.6 +/- 0.4 in the groups, respectively. The proportions of eicosapentaenoic and docosahexaenoic acids in serum lipids increased in the fatty fish group only (P < 0.05). Systolic and diastolic blood pressure levels decreased in the lean fish group (0 vs. 8 week: 3.5 +/- 3.2 and 4.6 +/- 3.6%, respectively, P < 0.05). Serum total triglyceride concentration did not significantly change. HDL cholesterol concentration change differed among groups but without significant post hoc differences. Apolipoprotein A-1 concentration decreased in the control group (0 vs. 8 week, P < 0.05). Coagulation factors, 25-hydroxy vitamin D, and heart rate variability (24 h Holter) did not change among the groups. Conclusions: Our results suggest that intake of lean fish at least four times per week could reduce blood pressure levels in CHD patients. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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