Pyoderma gangrenosum as a cause of splenomegaly and association with a T-cell clone.
The spectrum of clinical presentation of haematological disease is wide. We highlight two features of this principle: a rare cause of a ‘haematological’ presentation and a possible haematological cause of a disease not normally considered as such. A case of systemic pyoderma gangrenosum presented wi...
| Publicado en: | Clinical & Laboratory Haematology Vol. 27; no. 6; pp. 402 - 405 |
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| Autores principales: | , , |
| Formato: | case study tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Dec2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | The spectrum of clinical presentation of haematological disease is wide. We highlight two features of this principle: a rare cause of a ‘haematological’ presentation and a possible haematological cause of a disease not normally considered as such. A case of systemic pyoderma gangrenosum presented with splenomegaly in the absence of a rash. A clonal γ- and β-T-cell receptor rearrangement was demonstrated. Such clones may be a general phenomenon involved in the pathogenesis of this condition. |
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