Engineering the gut microbiota to treat hyperammonemia.

Increasing evidence indicates that the gut microbiota can be altered to ameliorate or prevent disease states, and engineering the gut microbiota to therapeutically modulate host metabolism is an emerging goal of microbiome research. In the intestine, bacterial urease converts host-derived urea to am...

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Detalles Bibliográficos
Publicado en:Journal of Clinical Investigation Vol. 125; no. 7; pp. 2841 - 2851
Autores principales: Shen, Ting-Chin David, Albenberg, Lindsey, Bittinger, Kyle, Chehoud, Christel, Chen, Ying-Yu, Judge, Colleen A, Chau, Lillian, Ni, Josephine, Sheng, Michael, Lin, Andrew, Wilkins, Benjamin J, Buza, Elizabeth L, Lewis, James D, Daikhin, Yevgeny, Nissim, Ilana, Yudkoff, Marc, Bushman, Frederic D, Wu, Gary D
Formato: Journal Article
Publicado: American Society for Clinical Investigation Jul2015
Acceso en línea:Ver este registro en EBSCOhost