Engineering the gut microbiota to treat hyperammonemia.

Increasing evidence indicates that the gut microbiota can be altered to ameliorate or prevent disease states, and engineering the gut microbiota to therapeutically modulate host metabolism is an emerging goal of microbiome research. In the intestine, bacterial urease converts host-derived urea to am...

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Bibliographic Details

Published in:	Journal of Clinical Investigation Vol. 125; no. 7; pp. 2841 - 2851
Main Authors:	Shen, Ting-Chin David, Albenberg, Lindsey, Bittinger, Kyle, Chehoud, Christel, Chen, Ying-Yu, Judge, Colleen A, Chau, Lillian, Ni, Josephine, Sheng, Michael, Lin, Andrew, Wilkins, Benjamin J, Buza, Elizabeth L, Lewis, James D, Daikhin, Yevgeny, Nissim, Ilana, Yudkoff, Marc, Bushman, Frederic D, Wu, Gary D
Format:	Journal Article
Published:	American Society for Clinical Investigation Jul2015
Online Access:	View this record in EBSCOhost