Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.

Guanylin (GN) and uroguanylin (UGN), through activation of guanylyl cyclase C (GCC), serve to control intestinal fluid homeostasis. Both peptides are produced in the intestinal epithelium, but their cellular origin has not been fully charted. Using quantitative PCR and an improved in situ hybridizat...

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Bibliographic Details

Published in:	Histochemistry & Cell Biology Vol. 146; no. 4; pp. 445 - 456
Main Authors:	Ikpa, Pauline, Sleddens, Hein, Steinbrecher, Kris, Peppelenbosch, Maikel, Jonge, Hugo, Smits, Ron, Bijvelds, Marcel
Format:	Journal Article
Published:	Springer Nature Oct2016
Online Access:	View this record in EBSCOhost