Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.

Guanylin (GN) and uroguanylin (UGN), through activation of guanylyl cyclase C (GCC), serve to control intestinal fluid homeostasis. Both peptides are produced in the intestinal epithelium, but their cellular origin has not been fully charted. Using quantitative PCR and an improved in situ hybridizat...

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Publicado en:Histochemistry & Cell Biology Vol. 146; no. 4; pp. 445 - 456
Autores principales: Ikpa, Pauline, Sleddens, Hein, Steinbrecher, Kris, Peppelenbosch, Maikel, Jonge, Hugo, Smits, Ron, Bijvelds, Marcel
Formato: Journal Article
Publicado: Springer Nature Oct2016
Acceso en línea:Ver este registro en EBSCOhost