Postprandial insulin and glucose levels are reduced in healthy subjects when a standardised breakfast meal is supplemented with a filtered sugarcane molasses concentrate.
Purpose: A phytochemical- and mineral-rich filtered sugarcane molasses concentrate (FMC), when added to carbohydrate-containing foods as a functional ingredient, lowers postprandial blood glucose and insulin responses. We hypothesised that this beneficial effect would also occur if FMC was administe...
| Published in: | European Journal of Nutrition Vol. 55; no. 8; pp. 2365 - 2377 |
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| Main Authors: | , , , |
| Format: | equations & formulas research tables/charts randomized controlled trial Journal Article |
| Published: |
Springer Nature
Dec2016
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=119755060&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 119755060 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Dec2016 vid: 55 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 119755060 119755060 119755060 10.1007/s00394-015-1043-6 119755060 ppf: 2365 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Postprandial insulin and glucose levels are reduced in healthy subjects when a standardised breakfast meal is supplemented with a filtered sugarcane molasses concentrate. aug: au: Ellis, Timothy Wright, Alison Clifton, Peter Ilag, Leodevico affil: Horizon Science Pty. Ltd. , 6/84-90 Lakewood Blvd. Braeside 3195 Australia sug: subj: Postprandial Period Blood Glucose Metabolism Insulin Blood Plant Extracts Pharmacodynamics Human Randomized Controlled Trials Random Assignment Single-Blind Studies Crossover Design Australia Plants, Medicinal Phytochemicals Pharmacodynamics Minerals Pharmacodynamics Dietary Supplementation Breakfast Dose-Response Relationship, Drug Body Mass Index Evaluation Insulin Resistance Adolescence Young Adult Adult Male Female Descriptive Statistics Mathematics Clinical Assessment Tools Power Analysis Effect Size Analysis of Variance Repeated Measures Pearson's Correlation Coefficient Data Analysis Software P-Value Post Hoc Analysis Dietary Carbohydrates Administration and Dosage Adolescent: 13-18 years Adult: 19-44 years Male Female ab: Purpose: A phytochemical- and mineral-rich filtered sugarcane molasses concentrate (FMC), when added to carbohydrate-containing foods as a functional ingredient, lowers postprandial blood glucose and insulin responses. We hypothesised that this beneficial effect would also occur if FMC was administered as an oral supplement taken before a meal. Methods: This study measured the postprandial glucose and insulin responses elicited by different doses of FMC administered immediately prior to a standard breakfast to healthy subjects. Each subject was given three or five breakfast meals once, on different days. The composition of the meals was identical, except for the addition of either placebo syrup (test meal 1) or increasing doses of FMC (test meals 2-5). Results: The plasma glucose concentration curves were similar for the five test meals. Plasma insulin curves were lowered in a dose-dependent manner. Stratifying subjects based on age, BMI and insulin resistance showed greater effects of low doses of FMC on lowering insulin responses in those subjects with potentially greater insulin resistance. When insulin response is standardised to amount of carbohydrate in the meal/dose combination, the reduction in response is linear and inversely proportional to the FMC dose. Conclusions: FMC shows promise as an agent that can reduce insulin responses and lessen the load on the pancreatic beta cells. pubtype: Academic Journal doctype: equations & formulas research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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